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KMID : 1098420040120040273
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Korean Journal of Medicinal Crop Science
2004 Volume.12 No. 4 p.273 ~ p.278
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Improvement of Anticancer Activation of Ultrasonificated Extracts from Acanthopanax senticosus Harms, Ephedra sinica Stapf, Rubus coreanus Miq. and Artemisia capillaris Thunb
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Park JIn-Hong
Kim Dae-Ho
Lee Hyeon-Yong
Seong Nak-Sul
Bang Jin-Ki
Chung Hae-Gon
Mun Hyoung-Chul
Lee Hyun-Soo
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Abstract
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The anticancer activities of the extracts from Acanthopanax senticosus Harms, Ephedra sinica Stapf, Rubus coreanus Miq and Artemisia capillaris Thunb were compared according to extract systems. About 70% of the growth of human hepatocarcinoma cancer cell was inhibited in adding 1.0 mg/ml of the water extract from Rubus coreanus Miq with ultrasonification at 60^{circ}C. The growth of human normal lung cell was limited to 25% in adding the extracts with ultrasonification at 60^{circ}C. The effect of extracts obtained by only water and with ultrasonification on different of human promyelocytic leukemia cells was also observed.
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KEYWORD
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Acanthopanax senticosus, Ephedra sinica, Rubus coreanus, Artemisia capillaris, ultrasonification, HL-60, differentiation, anticancer activation
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